A Case Study On “Ondine's Curse: A Challenging Case of Congenital Central Hypoventilation Syndrome

Yerni Kumar B; Pavani M; Naveen Babu Yelabilli

Authors

B. Yerni Kumar Assistant Professor, Department of Pharmacology, Avanthi Institute of Pharmaceutical Sciences,
M. Pavani Associate Professor Department of Biotechnology, Srinivasarao college of Pharmacy
Yelabilli Naveen Babu Avanthi Institute of Pharmaceutical Sciences, Cherukupally, Vizianagaram, Andhra Pradesh.

Keywords:

Ondine's Curse, PHOX2B gene, Hypoventilation, Genetic disorder, Managementstrategies

Abstract

Congenital Central Hypoventilation Syndrome (CCHS) is also known as Ondine's Curse. A rare hereditary condition known as congenital central hypoventilation syndrome (CCHS) affects babies and is evidenced by breathing difficulties during sleep without apparent respiratory warning manifestations. It is a globally underreported illness caused by a mutation in the PHOX2B gene. Affected people are increasingly able to endure life to adulthood due to increased survival rates that were achieved by early detection and care. The clinical characteristics, diagnostic difficulties, and management strategies for CCHS are covered in the current study.

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