Diabetic Retinopathy: Clinical Findings and Management

Authors

  • Bonthagarla Bhargavi Priyadarshini Institute of pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur -522017, Andhra Pradesh, India.
  • Sahaja Duggirala Priyadarshini Institute of pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur -522017, Andhra Pradesh, India.
  • Chandu Babu Rao Priyadarshini Institute of pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur -522017, Andhra Pradesh, India.
  • Budagala Gayathri Priyadarshini Institute of pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur -522017, Andhra Pradesh, India.

DOI:

https://doi.org/10.47957/ijciar.v7i2.173

Keywords:

diabetic retinopathy (DR), vision loss, edema, complications

Abstract

Diabetic retinopathy (DR) is a global source of visual loss and a consequence of diabetes. One of the most common metabolic disorders (DMs), diabetes mellitus (DM) affects people's ability to lead healthy lives worldwide and can have mild to severe secondary effects. Diabetic retinopathy (DR), which damages the retina and may result in blindness, is one of the secondary consequences of diabetes mellitus (DM). Although there may be other ocular problems associated with diabetes, diabetic retinopathy and cataracts are the primary causes of vision loss in DM. Patients with diabetes frequently experience severe retinal capillary aneurysms, haemorrhage, and edoema. These conditions might eventually result in diabetic macular edoema (DME) and non-proliferative or proliferative diabetic retinopathy (NPDR or PDR).Our goal in this study is to give a thorough overview of the epidemiology, pathophysiology, and potential treatment options of diabetic retinopathy, as well as how it progresses.

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References

Antonetti DA, Silva PS, Stitt AW. Current understanding of the molecular and cellular pathology of diabetic retinopathy. Nature Reviews Endocrinology. 2021 Apr;17(4):195-206. https://pubmed.ncbi.nlm.nih.gov/33469209/ DOI: https://doi.org/10.1038/s41574-020-00451-4

Bourne RR, Flaxman SR, Braithwaite T, Cicinelli MV, Das A, Jonas JB, Keeffe J, Kempen JH, Leasher J, Limburg H, Naidoo K. Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and meta-analysis. The Lancet Global Health. 2017 Sep 1;5(9):e888-97.

https://pubmed.ncbi.nlm.nih.gov/28779882/

Bodansky HJ, Cudworth AG, Whitelocke RA, Dobree JH. Diabetic retinopathy and its relation to type of diabetes: review of a retinal clinic population. British Journal of Ophthalmology. 1982 Aug 1;66(8):496-9. https://pubmed.ncbi.nlm.nih.gov/7049224/ DOI: https://doi.org/10.1136/bjo.66.8.496

Avinash M, Suryaprabha M, Sreekanth N, Dineshreddy B, Baburao CH. Advanced and Recent Emerging Trends in Insulin Dru g Delivery Systems. International Journal of Bio-Pharma Research. 2012;1.

Ramalingam P, Reddy YP, Kumar KV, Chandu BR, Rajendran K. Evaluation of metformin hydrochloride in Wistar rats by FTIR-ATR spectroscopy: A convenient tool in the clinical study of diabetes. Journal of natural science, biology, and medicine. 2014 Jul;5(2):288. DOI: https://doi.org/10.4103/0976-9668.136168

Chahal N, Rana M, Dhawan A, Gulia S. Assessment of frequency of occurrence of malocclusion among known paediatric population: a clinical study. Journal of Advanced Medical and Dental Sciences Research. 2018 Aug 1;6(8):37-9.

Vennela B, Shirisha V, Rao CB, Gullapalli V, Batsala M. Current and Future Strategies for Therapy of Pancreatic Cancer. International Journal of Research in Pharmacy and Medicine. 2012;2(3):728-40.

Early Treatment Diabetic Retinopathy Study Research Group. Early treatment diabetic retinopathy study report number 1; Photocoagulation for diabetic macular edema. Arch Ophthalmol. 1985;103:1796-806. https://pubmed.ncbi.nlm.nih.gov/2866759/ DOI: https://doi.org/10.1001/archopht.1985.01050120030015

L'Esperance FA, James WA. Diabetic Retinopathy: Clinical evaluation and management. (No Title). 1981.

Jarrett J, Stewart T, Rogers L. Diabetes mellitus I: Diagnosis and initial management. British Medical Journal (Clinical research ed.). 1981 Sep 9;283(6292):647. https://www.sciencedirect.com/science/article/abs/pii/S0140673679914892 DOI: https://doi.org/10.1136/bmj.283.6292.647-a

Jervell J, Moe N, Skjaeraasen J, Blystad W, Egge K. Diabetes mellitus and pregnancy—management and results at Rikshospitalet, Oslo, 1970–1977. Diabetologia. 1979 Mar; 16:151-5. https://pubmed.ncbi.nlm.nih.gov/428684/ DOI: https://doi.org/10.1007/BF01219791

Jerneld B, Algvere P. Relationship of duration and onset of diabetes to prevalence of diabetic retinopathy. American journal of ophthalmology. 1986 Oct 1;102(4):431-7. https://www.sciencedirect.com/science/article/abs/pii/0002939486900693 DOI: https://doi.org/10.1016/0002-9394(86)90069-3

KORNERUP T. Studies in diabetic retinopathy: an investigation of 1,000 cases of diabetes. Acta Medica Scandinavica. 1955 Jan 12;153(2):81-101. https://pubmed.ncbi.nlm.nih.gov/13292179/ DOI: https://doi.org/10.1111/j.0954-6820.1955.tb18208.x

Leasher JL, Bourne RR, Flaxman SR, Jonas JB, Keeffe J, Naidoo K, Pesudovs K, Price H, White RA, Wong TY, Resnikoff S. Global estimates on the number of people blind or visually impaired by diabetic retinopathy: a meta-analysis from 1990 to 2010. Diabetes care. 2016 Sep 1;39(9):1643-9. https://pubmed.ncbi.nlm.nih.gov/27555623/ DOI: https://doi.org/10.2337/dc15-2171

Published

30-06-2024

How to Cite

Bonthagarla, B., Duggirala, S., Chandu, B. R., & Budagala, G. (2024). Diabetic Retinopathy: Clinical Findings and Management. International Journal of Current Innovations in Advanced Research, 7(2), 1–27. https://doi.org/10.47957/ijciar.v7i2.173

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Review Articles

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