Role of Microneedle Technology in Transdermal Drug Delivery System

Kavya Kodirekkala

Authors

Kodirekkala Kavya Priyadarshini Institute of pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur -522017, Andhra Pradesh, India.

Keywords:

Microneedles, Transdermal drug delivery, Administration, Stratum Corneum, Application

Abstract

In order to safely, noninvasively, and painlessly transfer medications into the skin, microneedle (MN) transdermal drug delivery systems have undergone significant development. Newer production processes have led to the development of different varieties of MNs over the past few decades. In summary, the morphological characteristics of MNs can be categorized as solid, coated, dissolved, or hollow, according on the drug delivery strategies used for transfer: "shove and patch," "coat and poke," "shove and release," and "poke and flow." Other features of microneedles depend on their composition and design. Despite the benefits of using the skin to deliver drugs, the appearance of the stratum corneum—the topmost layers of dead cells—seriously restricts practical drug delivery through the skin. Utilizing silicon, metals, polymers, or polysaccharides, solid-coated microneedles can be used to puncture the outer layer of skin after application and popularization. Microneedles are manufactured using microelectromechanical systems.

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